|
|
4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-formyl-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + H2O + ferricytochrome_b5
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-16
|
|
|
|
4alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-formyl-5alpha-cholesta-8-en-3beta-ol + H2O + ferricytochrome_b5
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-21
|
|
|
|
5alpha-Cholest-7-en-3beta-ol + ferricytochrome_b5 + O2 + H+ <=> 7-dehydrocholesterol + ferricytochrome_b5 + H2O
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
| |
BRENDA:
BS258666;
BS432737
KEGG:
R07215
MetaCyc:
1.14.21.6-RXN
SABIO-RK:
14442
|
|
|
|
5alpha-Cholest-7-en-3beta-ol <=> 5alpha-cholesta-8-en-3beta-ol
|
5.3.3.5
cholestenol Delta-isomerase
|
–
|
| |
BRENDA:
BR3
KEGG:
R03353
MetaCyc:
RXN66-25
|
|
|
|
24,25-dihydrolanosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 8-lanostene-3beta,32-diol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-11
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8-en-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + H2O + ferricytochrome_b5
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-15
|
|
|
|
8-lanostene-3beta,32-diol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8-en-3beta-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-12
|
|
|
|
4alpha-formyl-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + H2O + ferricytochrome_b5
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-17
|
|
|
|
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-cholesta-8-en-3-one + NADPH + CO2
|
1.1.1.170
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
| |
BRENDA:
BS422641
MetaCyc:
RXN66-18
|
|
|
|
4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8-en-3beta-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-13
|
|
|
|
4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 5alpha-cholesta-8-en-3-one + CO2 + NADPH
|
1.1.1.170
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
| |
BRENDA:
BS422643
MetaCyc:
RXN66-23
|
|
|
|
24,25-dihydrolanosterol + NADP+ <=> lanosterol + NADPH + H+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
| |
BRENDA:
BS189402
KEGG:
R03689
MetaCyc:
RXN66-10
|
|
|
|
4alpha-methyl-5alpha-cholesta-8-en-3-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol + H2O + ferricytochrome_b5
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-20
|
|
|
|
5alpha-cholesta-8-en-3beta-ol + NADP+ <=> H+ + 5alpha-cholesta-8-en-3-one + NADPH
|
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
|
–
|
| |
MetaCyc:
RXN66-24
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> H+ + 4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol + NADPH
|
1.3.1.70
Delta14-sterol reductase
|
–
|
| |
BRENDA:
BS189391
MetaCyc:
RXN66-14
|
|
|
|
cholesterol + NADP+ <=> 7-dehydrocholesterol + NADPH + H+
|
1.3.1.21
7-dehydrocholesterol reductase
|
–
|
| |
BRENDA:
BR33764
KEGG:
R01456
MetaCyc:
RXN66-323
SABIO-RK:
1634
|
|
|
|
4alpha-methyl-5alpha-cholesta-8-en-3-ol + NADP+ <=> 4alpha-methyl-5alpha-cholesta-8-en-3-one + NADPH + H+
|
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
|
–
|
| |
MetaCyc:
RXN66-19
|
|
|
|
4alpha-formyl-5alpha-cholesta-8-en-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + H2O + ferricytochrome_b5
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-22
|
|
